Miracle Drug is about the intersection of medicine and miracle, via. poet/author Christopher Nolan. Bono introduced the song at U2's surprise concert here in Brooklyn, NY on November 22, 2004 by saying:
We come from the North side o' Dublin, went to a school called Mount Temple Comprehensive. That's where we met. When we were leaving this new student came in. He was a boy completely paralyzed, nothing moving. He was born ... w/o oxygen, but he had something in his eyes, this light in his eyes. So his mother believed in him, that he was awake, that he was conscious... So she used to read to him ... teach him. Then when he was 13 years old, they discovered this little drug which allowed him to move his neck one inch ... and with that he was able to type with this little thing they attached to his head. Turns out, he'd been writing stuff in his head for years, this poetry, beautiful poetry - put out this book called "Dam-Burst of Dreams" ... his first poem was called "I Learned To Bow" where he thanked God for the gift of science and medicine. Of course, science, medicine & god are all the same thing. They should always be the same thing. His name is Christopher Nolan, this is called "Miracle Drug..."